HPL Full Form

HPL Full Form


HPL Full Form
Full Form of HPL in Medical
HPL refers to “Human placental lactogen” or full form of  HPL is “Human placental lactogen”  
HPL definition
HPL(Human placental lactogenis a placental protein hormone secreted by the cytotrophoblast that rises steadily and peaks at 34 weeks of gestation.
Endcrinological changes during pregnancy
Human Chorionic Somatomammotropin
Human chorionic somatomammotropin (HCS), originally known as Human placental lactogen (Higashi, 1961; Josimovich and Maclaren, 1962), has both growth hormone-like and lactogenic activity.
Human Placental Lactogen
Human placental lactogen (hPL) is a single-chain polypeptide of 191 amino acids. HPL is very similar to human growth hormone (GH) but has only 3% of its activity. Its lactogenic contribution in human pregnancy is uncertain. Its half-life is approximately 15 min. The HPL level in the maternal circulation is correlated with fetal and placental weight, steadily increasing until it plateaus in the last month of pregnancy (5–7 mg mL− 1). There is no circadian variation and only minute amounts enter the fetal circulation.
Human Placental Lactogen
HPL(Human placental lactogen) (HPL) is a placental protein hormone secreted by the syncytiotrophoblast that rises steadily and peaks at 34 weeks of gestation. hPL shares structural homology with growth hormone (GH) and prolactin and can bind both receptors. In concert with human placental growth hormone (hPGH), hPL modulates maternal metabolism to meet the energy requirements of the developing fetus. Specifically, HPL and HPGH induce peripheral insulin resistance and thereby reduce maternal glucose utilization, while concomitantly increasing maternal lipolysis.